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Senior Clinical Data Engineer

Architecting secure, compliant, and scalable data ecosystems for Pharma & Healthcare.

Nicholas Ruffin, Senior Clinical Data Engineer

I specialize in building high-performance data infrastructure for regulated industries. My recent work includes architecting a data monetization platform that drives $7M+ in annual revenue and engineering de-identification pipelines for 4.8 billion clinical records.

From raw data ingestion to secure analytics delivery, I leverage the modern data stack—Snowflake, Airflow, AWS, and Python—to turn massive datasets into actionable business value, all while ensuring strict HIPAA/GDPR compliance.

  • Monetization & Strategy: Tokenization (Datavant), Privacy Engineering, Revenue-Generating Pipelines
  • Cloud Architecture: Snowflake Optimization, AWS (S3, Lambda, EventBridge, MWAA)
  • Orchestration: Advanced Airflow DAGs, Python Automation, CI/CD (GitHub Actions)
  • Compliance: HIPAA-safe handling of PII/PHI, De-identification frameworks

Interested in my background or architecture?
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CAREER HISTORY

Experience & Background

Proven track record in high-stakes clinical and enterprise data environments.

Senior Clinical Data Engineer

RedSail Technologies Feb 2025 - Present

Leading data monetization and privacy engineering for pharmaceutical datasets.

  • Designed a data monetization platform driving $7M+ in annual revenue through secure PII tokenization (Datavant).
  • Engineered de-identification pipelines ensuring full HIPAA compliance for large-scale clinical data sharing.
  • Automated ETL for 4.8 billion records (3M daily transactions) using Snowflake stored procedures and Airflow.
  • Built end-to-end Python orchestration for S3 extraction and Snowflake ingestion, deployed via GitHub Actions.

Lead Data Integration Developer

Nimble Solutions Aug 2021 - Feb 2025
  • Led microservices architecture development for AR workflow solutions using .NET/C#.
  • Integrated 50+ data sources, improving case processing efficiency by 32+ cases per rep.
  • Implemented CI/CD pipelines in Azure DevOps with 90%+ code coverage.
  • Architected Azure Function Apps for high-volume claim status retrieval via REST APIs.

Full Stack Developer

Core & Main Jun 2017 - Aug 2021
  • Developed enterprise .NET/SQL applications and authentication systems.
  • Optimized stored procedures for efficient large-scale data management.